DVD disc contain VOB files, each VOB is usually 1GB file that contains the actual video. It is possible to upload each VOB using the Media Agent or the web batch uploader.
The smaller files are usually menus and will not function after uploading. VOB doesn't start or end according to the DVD chapters therefore it is better to rip the DVD before uploading it. Search for "How to Rip a DVD".
Uploading using the web uploader will take significantly more time than with a Media Agent since the latter will encode the video on your desktop and upload only the encoded file.